Perhaps the greatest milestone in 2016 came when Dr. Uday Bhanu Maachani established two gliomatosis cerebri cell cultures from living patients. From one of these lines he created a xenograft: A mouse model with a GC tumor sampled from an actual patient. This is the only animal model anywhere in the world with a GC tumor cultured from a patient.
Why is this so exciting? The promise at the heart of precision medicine is one-to-one matching of disease and cure—creating a xenograft from a patient tissue sample allows us to test promising treatments against that individual’s exact tumor in a living model. We are tremendously excited by this advance, even as we face our next hurdle: identifying and gaining access to a drug with the best chance of destroying that tumor.