The Children’s Brain Tumor Project at Weill Cornell Medicine

The Children’s Brain Tumor Project is a research effort at the Weill Cornell Pediatric Brain and Spine Center, co-directed by Dr. Mark Souweidane and Dr. Jeffrey Greenfield. The Children’s Brain Tumor Project has a single goal: to bring hope to the hundreds of patients and families each year who confront the heartbreaking diagnoses of rare and inoperable pediatric brain tumors.

Gliomatosis cerebri, thalamic gliomas, diffuse intrinsic pontine glioma (DIPG), craniopharyngioma, and ependymoma are just a few examples of the devastating brain tumors that strike children and adolescents. We focus on studying these tumor types because rare and inoperable tumors are most often neglected in the research landscape due to the lack of funding and support that research scientists need to find cures.



To improve the outcome for children with brain tumors by advancing scientific discovery and clinical research that focuses on targeted therapy, effective drug delivery, and low treatment-related toxicity.


The CBTP leverages next-generation approaches that explore diseases and potential solutions from four strategic pillars of research in an effort to accelerate progress and save the lives of children.


Meet the Principle Investigators at the CBTP lab and learn more about how our dedicated team of neuroscientists work together to uncover cures.

“Dr. Mark Souweidane has given me tremendous hope that DIPG will be cured in my lifetime. In memory of my son, Cristian, I will continue to support his research until that day comes.”

John Rivera • Founder, The Cristian Rivera Foundation