Our mission is to improve the outcome for children with brain tumors by advancing scientific discovery and clinical research that focuses on:

  • targeted therapy

  • effective drug delivery, and

  • low treatment-related toxicity

The Children’s Brain Tumor Project has a single goal: to bring hope to children and their families who are confronted with the diagnosis of a rare and often incurable brain tumor.


Rare pediatric brain tumors have been grossly neglected in the research landscape for years, and the Children’s Brain Tumor Project at Weill Cornell Medicine is emerging as the go-to research entity that has established a niche in developing new protocols for treating these children. We believe children from all over the world should have access to innovative options beginning with world-class, minimally invasive surgery, and extending into targeted treatment options centered on precision medicine and drug delivery approaches that would not otherwise be available to them.



Basic research and early clinical trials validate new therapies that may effectively address the critical needs of our patients. Our team of experts are committed to bringing discoveries from “bench to bedside.”


Collaboration is essential to advancing research, and the CBTP proudly collaborates with national and international consortiums to share data, tumor samples, and cell lines — and to design, develop and expand on clinical trials.


We are proud to be part of the Children’s Oncology Group, offering clinical trials in partnership with hundreds of hospitals around the world, in addition to participating in clinical trials developed here at Weill Cornell Medicine.


The CBTP also founded and operates two pediatric brain tumor registries — the Gliomatosis Cerebri International Registry and the Thalamic Glioma Registry — which are providing a wealth of data to inform further investigation where there used to be none.

“Pediatric brain tumors are the most common solid tumors in children, and the most fatal pediatric cancer. We aim to change that statistic.”

Dr. Jeffrey Greenfield • Co-Founder, Weill Cornell Medicine Children’s Brain Tumor Project