PUBLICATIONS

ALL ACADEMIC PUBLICATIONS

Peer-reviewed publications validate research findings because they subject the authors scholarly work to a high level of scrutiny from other experts in the field who evaluate whether an article is suitable for publication. The volume of published work from the team at the Children’s Brain Tumor Project is a testament to the hard work and dedication of our lab team. Below is a just a selection of articles that our team has contributed to in recent years.

PEDIATRIC NEUROLOGY – NOVEMBER 2023

Esteban U. Arias-Stella, Cindy Campbell, David J. Pisapia MD, Carolina Cocito PhD, Sheila McThenia MD, Melanie Degliuomini MD, Jeffrey P. Greenfield MD, PhD, Yasmin Khakoo MD

JOURNAL OF HEMATOLOGY AND ONCOLOGY – NOVEMBER 2022
Phase 1 study of intraventricular 131I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies

Kim Kramer, Neeta Pandit-Taskar, Brian H Kushner, Pat Zanzonico, John L Humm, Ursula Tomlinson, Maria Donzelli, Suzanne L Wolden, Sophia Haque, Ira Dunkel, Mark M Souweidane, Jeffrey P Greenfield, Satish Tickoo, Jason S Lewis, Serge K Lyashchenko, Jorge A Carrasquillo, Bae Chu, Christopher Horan, Steven M Larson, Nai-Kong V Cheung, Shakeel Modak

PMID: 36371226 PMCID: PMC9655863

PEDIATRIC BLOOD AND CANCER – NOVEMBER 2022

Clinical outcomes of pediatric patients receiving multimodality treatment of second central nervous system relapse of neuroblastoma.

Tringale KR, Wolden SL, Casey DL, Kushner BH, Luo L, Pandit-Taskar N, Souweidane M, Cheung NV, Modak S, Basu EM, Kramer K. PMID: 36349892

NEOPLASIA – NOVEMBER 2022

The children’s brain tumor network (CBTN) – Accelerating research in pediatric central nervous system tumors through collaboration and open science.

Lilly JV, Rokita JL, Mason JL, Patton T, Stefankiewiz S, Higgins D, Trooskin G, Larouci CA, Arya K, Appert E, Heath AP, Zhu Y, Brown MA, Zhang B, Farrow BK, Robins S, Morgan AM, Nguyen TQ, Frenkel E, Lehmann K, Drake E, Sullivan C, Plisiewicz A, Coleman N, Patterson L, Koptyra M, Helili Z, Van Kuren N, Young N, Kim MC, Friedman C, Lubneuski A, Blackden C, Williams M, Baubet V, Tauhid L, Galanaugh J, Boucher K, Ijaz H, Cole KA, Choudhari N, Santi M, Moulder RW, Waller J, Rife W, Diskin SJ, Mateos M, Parsons DW, Pollack IF, Goldman S, Leary S, Caporalini C, Buccoliero AM, Scagnet M, Haussler D, Hanson D, Firestein R, Cain J, Phillips JJ, Gupta N, Mueller S, Grant G, Monje-Deisseroth M, Partap S, Greenfield JP, Hashizume R, Smith A, Zhu S, Johnston JM, Fangusaro JR, Miller M, Wood MD, Gardner S, Carter CL, Prolo LM, Pisapia J, Pehlivan K, Franson A, Niazi T, Rubin J, Abdelbaki M, Ziegler DS, Lindsay HB, Stucklin AG, Gerber N, Vaske OM, Quinsey C, Rood BR, Nazarian J, Raabe E, Jackson EM, Stapleton S, Lober RM, Kram DE, Koschmann C, Storm PB, Lulla RR, Prados M, Resnick AC, Waanders AJ.

PMID: 36335802

NEUROONCOLOGY – OCTOBER 2022

Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult brain tumor patients.

Miller AM, Szalontay L, Bouvier N, Hill K, Ahmad H, Rafailov J, Lee AJ, Rodriguez-Sanchez MI, Yildirim O, Patel A, Bale TA, Benhamida JK, Benayed R, Arcila ME, Donzelli M, Dunkel IJ, Gilheeney SW, Khakoo Y, Kramer K, Sait SF, Greenfield JP, Souweidane MM, Haque S, Mauguen A, Berger MF, Mellinghoff IK, Karajannis MA.

PMID: 35148412

PEDIATRIC BLOOD CANCER – SEPTEMBER 2022

A systematic literature review to identify ethical, legal, and social responsibilities of nonprofit organizations when funding clinical trials in pediatric cancer

Vasiliki Rahimzadeh, Susan Wolfert, Vickie Buenger, Cindy Campbell, Robin French, Donna Ludwinski, Amy Weinstein, Caitlyn Barrett

EPIGENOMICS – JUNE 2022

Developments in high throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens

Rachel E Yan, Jeffrey P Greenfield, Nadia Dahmane

PMID: 35574596

NEUROONCOLOGY – JUNE 2022

Phase II trial of response-based radiation therapy for patients with localized germinoma: a Children’s Oncology Group study.

Bartels U, Onar-Thomas A, Patel SK, Shaw D, Fangusaro J, Dhall G, Souweidane M, Bhatia A, Embry L, Trask CL, Murphy ES, MacDonald S, Wu S, Boyett JM, Leary S, Fouladi M, Gajjar A, Khatua S.

PMID: 34850169

JOURNAL OF NEUROONCOLOGY – MAY 2022

Quantifying intraventricular drug delivery utilizing programmable ventriculoperitoneal shunts as the intraventricular access device.

McThenia SS, Pandit-Taskar N, Grkovski M, Donzelli MA, Diagana S, Greenfield JP, Souweidane MM, Kramer K.J

PMID: 35403968

LANCET ONCOLOGY – MAY 2022

Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children’s Oncology Group.

Morana G, Shaw D, MacDonald SM, Alapetite C, Ajithkumar T, Bhatia A, Brisse H, Jaimes C, Czech T, Dhall G, Fangusaro J, Faure-Conter C, Fouladi M, Hargrave D, Harreld JH, Mitra D, Nicholson JC, Souweidane M, Timmermann B, Calaminus G, Bartels U, Bison B, Murray MJ.

PMID: 35489353

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY AND BIOLOGICAL PHYSICS – MAY 2022

A Phase 2 Trial of Response-Based Radiation Therapy for Localized Central Nervous System Germ Cell Tumors: Patterns of Failure and Radiation Dosimetry for Nongerminomatous Germ Cell Tumors.

Murphy ES, Dhall G, Fangusaro J, Bartels U, Fouladi M, Shaw D, Khatua S, Hughes CW, Panigraphy A, Ioakeim-Ioannidou M, Souweidane M, Morris D, Gajjar A, Wu S, Onar-Thomas A, Haas-Kogan DA, MacDonald SM.

PMID: 34990779

NEUROONCOLOGY ADVANCES – MARCH 2022

Utility of multimodality molecular profiling for pediatric patients with central nervous system tumors.

Rajappa P, Eng KW, Bareja R, Bander ED, Yuan M, Dua A, Bhanu Maachani U, Snuderl M, Pan H, Zhang T, Tosi U, Ivasyk I, Souweidane MM, Elemento O, Sboner A, Greenfield JP, Pisapia DJ.

PMID: 35475276 Free PMC article.

NEUROONCOLOGY – NOVEMBER 2021

Intracranial germ cell tumors in Adolescents and Young Adults: European and North American consensus review, current management and future development

D Frappaz, G Dhall, M J Murray, S Goldman, C Faure Conter, J Allen, R Kortmann, D Haas-Kogen, G Morana, J Finlay, J C Nicholson, Ute Bartels, M Souweidane, S Schöenberger, A Vasiljevic, P Robertson, A Albanese, C Alapetite, T Czech, C C Lau, P Wen, D Schiff, D Shaw, G Calaminus, E Bouffet

JOURNAL OF NEUROSURGERY PEDIATRICS – AUGUST 2021

Intraarterial delivery of bevacizumab and cetuximab utilizing blood-brain barrier disruption in children with high-grade glioma and diffuse intrinsic pontine glioma: results of a phase I trial

Heather J McCrea, Jana Ivanidze, Ashley O’Connor, Eliza H Hersh, John A Boockvar, Y Pierre Gobin, Jared Knopman, Jeffrey P Greenfield

MOLECULAR CELL BIOLOGY – JUNE 2021

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons

Chaomei Xiang 1, Karla K Frietze 1, Yingtao Bi 2, Yanwen Li 1, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E Mason, Ramana V Davuluri, Nadia Dahmane

JOURNAL OF NEUROSURGERY PEDIATRICS – MAY 2021

Evaluation of a patient-specific algorithm for predicting distribution for convection-enhanced drug delivery into the brainstem of patients with diffuse intrinsic pontine glioma.

Wembacher-Schroeder E, Kerstein N, Bander ED, Pandit-Taskar N, Thomson R, Souweidane MM

SCIENTIFIC REPORTS – OCTOBER 2020

Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images

Eric W Prince, Ros Whelan, David M Mirsky, Nicholas Stence, Susan Staulcup, Paul Klimo, Richard C E Anderson, Toba N Niazi, Gerald Grant, Mark Souweidane, James M Johnston , Eric M Jackson , David D Limbrick Jr, Amy Smith, Annie Drapeau, Joshua J Chern, Lindsay Kilburn, Kevin Ginn, Robert Naftel, Roy Dudley, Elizabeth Tyler-Kabara, George Jallo, Michael H Handler, Kenneth Jones, Andrew M Donson, Nicholas K Foreman, Todd C Hankinson

JOURNAL OF NEUROSURGERY PEDIATRICS – SEPTEMBER 2020

Repeat convection-enhanced delivery for diffuse intrinsic pontine glioma.

Bander ED, Ramos AD, Wembacher-Schroeder E, Ivasyk I, Thomson R, Morgenstern PF, Souweidane MM.

PMID: 32977309

SCIENTIFIC ADVANCES – JULY 2020

PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models.

Tosi U, Kommidi H, Adeuyan O, Guo H, Maachani UB, Chen N, Su T, Zhang G, Pisapia DJ, Dahmane N, Ting R, Souweidane MM

PMID: 32832670

PHARMACEUTICS – JULY 2020

Convection Enhanced Delivery for Diffuse Intrinsic Pontine Glioma: Review of a Single Institution Experience

by Umberto Tosi and Mark Souweidane

ACTA NEUROPATHOLOGICA COMMUNICATIONS – JUNE 2020

Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.

Pisapia DJ, Ohara K, Bareja R, Wilkes DC, Hissong E, Croyle JA, Kim JH, Saab J, MacDonald TY, Beg S, O’Reilly C, Kudman S, Rubin MA, Elemento O, Sboner A, Greenfield J, Mosquera JM.

PMID: 32493417

NEURO-ONCOLOGY ADVANCES – MAY 2020

Missing diversity in brain tumor trials.

Taha B, Winston G, Tosi U, Hartley B, Hoffman C, Dahmane N, Mason CE, Greenfield JP.

PMID: 32642711

ACTA NEUROPATHOLOGICA COMMUNICATIONS – May 2020

Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets

Eric Prince, Ros Whelan, Andrew Donson, Susan Staulcup, Astrid Hengartner, Trinka Vijmasi, Chibueze Agwu, Kevin O Lillehei, Nicholas K Foreman, James M Johnston, Luca Massimi, Richard C E Anderson, Mark M Souweidane, Robert P Naftel, David D Limbrick, Gerald Grant, Toba N Niazi, Roy Dudley, Lindsay Kilburn, Eric M Jackson, George I Jallo, Kevin Ginn, Amy Smith, Joshua J Chern, Amy Lee, Annie Drapeau, Mark D Krieger, Michael H Handler, Todd C Hankinson, Advancing Treatment for Pediatric Craniopharyngioma Consortium

PMID: 32404202 PMCID: PMC7222517

NEURO-ONCOLOGY – APRIL 2020

A Combined Approach of Convection-Enhanced Delivery of Peptide Nanofiber Reservoir to Prolong Delivery of DM1 for Diffuse Intrinsic Pontine Glioma Treatment.

Bellat V, Alcaina Y, Tung CH, Ting R, Michel A, Souweidane M, Law B.

PMID: 32301996

TRANSLATIONAL ONCOLOGY – FEB 2020

B7-H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric Central Nervous System Tumors.

Maachani UB, Tosi U, Pisapia DJ, Mukherjee S, Marnell CS, Voronina J, Martinez D, Santi M, Dahmane N, Zhou Z, Hawkins C, Souweidane MM. Download free PMC article here.

WORLD NEUROSURGERY – FEB 2020

Longitudinal Monitoring of Gd-DTPA Following Convection Enhanced Delivery in the Brainstem.

Tosi U, Souweidane MM.

PMID:32028001

NEUROSURGICAL FOCUS – JANUARY 2020

Deformational Changes After Convection-Enhanced Delivery in the Pediatric Brainstem
(Pediatric Brain Tumor: Evolving Treatment Strategies)

Bander ED, Tizi K, Wembacher-Schroeder E, Thomson R, Donzelli M, Vasconcellos E, Souweidane MM.

JOURNAL OF NEUROSURGERY PEDIATRICS – DECEMBER 2019

The Intersect of Neurosurgery with Diffuse Intrinsic Pontine Glioma

Kuzan-Fischer CM, Souweidane MM

FRONTIERS IN COMPUTATIONAL NEUROSCIENCE – DECEMBER 2019

Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of de novo Glioblastoma Patients.

Rathore S, Akbari H, Bakas S, Pisapia JM, Shukla G, Rudie JD, Da X, Davuluri RV, Dahmane N, O’Rourke DM, Davatzikos C.

PMID:31920606

NEURO-ONCOLOGY ADVANCES – MAY-DECEMBER 2019

Combined targeting of PI3K and MEK effector pathways via CED for DIPG therapy

Raymond Chang, Umberto Tosi, Julia Voronina, Oluwaseyi Adeuyan, Linda Y Wu, Melanie E Schweitzer, David J Pisapia, Oren J Becher, Mark M Souweidane, Uday B Maachani

JOURNAL OF CLINICAL ONCOLOGY – DECEMBER 2019

Phase II Trial of Response-Based Radiation Therapy for Patients With Localized CNS Nongerminomatous Germ Cell Tumors: A COG Study

Fangusaro J, Wu S, MacDonald S, Murphy E, Shaw D, Bartels U, Khatua S, Souweidane M, Lu HM, Morris D, Panigrahy A, Onar-Thomas A, Fouladi M, Gajjar A, Dhall G.

PMID: 31786541

ACTA NEUROPATHOLOGIA COMMUNICATIONS – NOVEMBER 2019

Immune landscapes associated with different glioblastoma molecular subtypes.

Martinez-Lage M, Lynch TM, Bi Y, Cocito C, Way GP, Pal S, Haller J, Yan RE, Ziober A, Nguyen A, Kandpal M, O’Rourke DM, Greenfield JP, Greene CS, Davuluri RV, Dahmane N.2019 Nov 29;7(1):203. doi: 10.1186/s40478-019-0803-6.

PMID: 31815646

JOURNAL OF CLINICAL ONCOLOGY – NOVEMBER 2019

Phase II Study of Nonmetastatic Desmoplastic Medulloblastoma in Children Younger Than 4 Years of Age: A COG Study

Lafay-Cousin L, Bouffet E, Strother D, Rudneva V, Hawkins C, Eberhart C, Horbinski C, Heier L, Souweidane M, Williams-Hughes C, OnarThomas A, Billups CA, Fouladi M, Northcott P, Robinson G, Gajjar A.

PMID: 31774708

JCO PRECISION ONCOLOGY – SEPTEMBER 2019

Integrative Molecular Analysis of Patients With Metastatic Cancer

Sailer V, Eng KW, Zhang T, Bareja R, Pisapia DJ, Sigaras A, Bhinder B, Romanel A, Wilkes D, Sticca E, Cyrta J, Rao R, Sahota S, Pauli C, Beg S, Motanagh S, Kossai M, Fontunge J, Puca L, Rennert H, Zhaoying Xiang J, Greco N, Kim R, MacDonald TY, McNary T, Blattner-Johnson M, Schiffman MH, Faltas BM, Greenfield JP, Rickman D, Andreopoulou E, Holcomb K, Vahdat LT, Scherr DS, van Besien K, Barbieri CE, Robinson BD, Fine HA, Ocean AJ, Molina A, Shah MA, Nanus DM, Pan Q, Demichelis F, Tagawa ST, Song W, Mosquera JM, Sboner A, Rubin MA, Elemento O, Beltran H.

PMID: 31592503

ONCOLOGY TIMES – NOVEMBER 2019

2019 Excellence in Oncology Award—Dr. Mark Souweidane Honorable Mention. Direct Delivery to Brainstem in Rare Pediatric Tumor Proves Safe.

AUTHOR: Chuck Holt

JOURNAL OF NEUROSURGERY PEDIATRICS – SEPTEMBER 2019

Developing a 3D composite training model for cranial remodeling.

Cheng D, Yuan M, Perera I, O’Connor A, Evins AI, Imahiyerobo T, Souweidane M, Hoffman C.

MOLECULAR PHARMACOLOGY – AUGUST 2019

An [18F]-Positron Emitting Fluorophore Allows Safe Evaluation of Small Molecule Distribution in CSF, CSF Fistulas, and CNS Device Placement.

Guo H, Kommidi H, Maachani UB, Voronina JC, Zhang W, Magge RS, Ivanidze J, Wu AP, Souweidane MM, Aras O, Ting R.

PMID: 31290330

ACTA NEUROCHIRURGICA (WIEN) – AUGUST 2019

Endonasal surgery for suprasellar germ cell tumors: two cases and review of the literature.

Arnaout MM, Gerges MM, Cummock MD, El Asri AC, Greenfield JP, Anand VK, Schwartz TH.

OXFORD ACADEMIC NEURO-ONCOLOGY ADVANCES – MAY 2019

Combined Targeting of PI3K and MEK Effector Pathways via CED for DIPG Therapy

Raymond Chang, Umberto Tosi, Julia Voronina, Oluwaseyi Adeuyan, Y Linda Wu, Melanie E Schweitzer, David J Pisapia, Oren J Becher, Mark M Souweidane, Uday B Maachani. Read more about the paper here.

ACS CHEMICAL NEUROSCIENCE – MAY 2019

Real-Time, in Vivo Correlation of Molecular Structure with Drug Distribution in the Brain Striatum Following Convection Enhanced Delivery.

Tosi U, Kommidi H, Bellat V, Marnell CS, Guo H, Adeuyan O, Schweitzer ME, Chen N, Su T, Zhang G, Maachani UB, Pisapia DJ, Law B, Souweidane MM, Ting R.ACS Chem Neurosci. 2019 May 15;10(5):2287-2298. doi: 10.1021/acschemneuro.8b00607. Epub 2019 Mar 6.

PMID:30838861

ACTA NEUROPATHOLOGICAL COMMUNICATIONS – APRIL 2019

Transcriptome signatures associated with meningioma progression.

Viaene AN, Zhang B, Martinez-Lage M, Xiang C, Tosi U, Thawani JP, Gungor B, Zhu Y, Roccograndi L, Zhang L, Bailey RL, Storm PB, O’Rourke DM, Resnick AC, Grady MS, Dahmane N.

PMID:31039818

NATURE – JANUARY 2019

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.

Miller AM, Shah RH, Pentsova EI, Pourmaleki M, Briggs S, Distefano N, Zheng Y, Skakodub A, Mehta SA, Campos C, Hsieh WY, Selcuklu SD, Ling L, Meng F, Jing X, Samoila A, Bale TA, Tsui DWY, Grommes C, Viale A, Souweidane MM, Tabar V, Brennan CW, Reiner AS, Rosenblum M, Panageas KS, DeAngelis LM, Young RJ, Berger MF, Mellinghoff IK.

Nature. 2019 Jan;565(7741):654-658. doi: 10.1038/s41586-019-0882-3. Epub 2019 Jan 23.

PMID: 30675060

NATURE – JANUARY 2019

¹⁸F-Radiolabeled Panobinostat Allows for Positron Emission Tomography Guided Delivery of a Histone Deacetylase Inhibitor.

Kommidi H, Tosi U, Maachani UB, Guo H, Marnell CS, Law B, Souweidane MM, Ting R.ACS Med Chem Lett. 2018 Jan 17;9(2):114-119. doi: 10.1021/acsmedchemlett.7b00471. eCollection 2018 Feb.

Nature. 2019 Jan;565(7741):654-658. doi: 10.1038/s41586-019-0882-3. Epub 2019 Jan 23.

PMID:30675060 FREE DOWNLOAD

JOURNAL OF NEUROSURGERY – DECEMBER 2018

Clinical tolerance of corticospinal tracts in convection-enhanced delivery to the brainstem.

Morgenstern PF, Zhou Z, Wembacher-Schröder E, Cina V, Tsiouris AJ, Souweidane MM

PMID: 30579270 DOI: 10.3171/2018.6.JNS18854

LANCET ONCOLOGY – AUGUST 2018

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.

Souweidane MM, Kramer K, Pandit-Taskar N, Zhou Z, Haque S, Zanzonico P, Carrasquillo JA, Lyashchenko SK, Thakur SB, Donzelli M, Turner RS, Lewis JS, Cheung NV, Larson SM, Dunkel IJ.Lancet Oncol. 2018 Aug;19(8):1040-1050. doi: 10.1016/S1470-2045(18)30322-X. Epub 2018 Jun 18. Erratum in: Lancet Oncol. 2018 Aug;19(8):e382.

PMID: 29914796

MOLECULAR THERAPY ONCOLYTICS – AUGUST 2018

Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.

Yin Y, Boesteanu AC, Binder ZA, Xu C, Reid RA, Rodriguez JL, Cook DR, Thokala R, Blouch K, McGettigan-Croce B, Zhang L, Konradt C, Cogdill AP, Panjwani MK, Jiang S, Migliorini D, Dahmane N, Posey AD Jr, June CH, Mason NJ, Lin Z, O’Rourke DM, Johnson LA.

PMID:30306125

NEURO-ONCOLOGY – JULY 2018

In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature.

Akbari H, Bakas S, Pisapia JM, Nasrallah MP, Rozycki M, Martinez-Lage M, Morrissette JJD, Dahmane N, O’Rourke DM, Davatzikos C.

PMID: 29617843

JOURNAL OF NEUROSURGERY – JULY 2018

Volume of distribution and clearance of peptide-based nanofiber after convection-enhanced delivery.

Singh R, Bellat V, Wang M, Schweitzer ME, Wu YL, Tung CH, Souweidane MM, Law B.J Neurosurg. 2018 Jul;129(1):10-18. doi: 10.3171/2017.2.JNS162273. Epub 2017 Sep 8.

PMID:28885119

NEUROONCOLOGY – JUNE 2018

TBIO-06. B7-H3 expression as a potential biomarker of prognosis and target in pediatric glial and non-glial CNS tumors.

Uday Bhanu Maachani, Zhiping Zhou, Daniel Martinez, Mariarita Santi, Nadia Dahmane, and Mark Souweidane.

PMCID: PMC6012773

COLD SPRING HARBOR MOLECULAR CASE STUDIES – APRIL 2018

Precision oncogenomics in pediatrics: a personal reflection.

Campbell C, Greenfield JP.Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: a002865. doi: 10.1101/mcs.a002865. Print 2018 Apr. Review.

PMID: 29610396. Free PMC Article

JOURNAL OF NUCLEAR MEDICINE – MARCH 2018

PARP-1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

Jannetti SA, Carlucci G, Carney B, Kossatz S, Shenker L, Carter LM, Salinas B, Brand C, Sadique A, Donabedian PL, Cunanan KM, Gönen M, Ponomarev V, Zeglis BM, Souweidane MM, Lewis JS, Weber WA, Humm JL, Reiner T.

JOURNAL OF NEUROONCOLOGY – MARCH 2018

Patterns of relapse for children with localized intracranial ependymoma.

De B, Khakoo Y, Souweidane MM, Dunkel IJ, Patel SH, Gilheeney SW, De Braganca KC, Karajannis MA, Wolden SL.J

PEDIATRIC BLOOD CANCER – JANUARY 2018

A phase II study of radioimmunotherapy with intraventricular ¹³¹ I-3F8 for medulloblastoma.

Kramer K, Pandit-Taskar N, Humm JL, Zanzonico PB, Haque S, Dunkel IJ, Wolden SL, Donzelli M, Goldman DA, Lewis JS, Lyashchenko SK, Khakoo Y, Carrasquillo JA, Souweidane MM, Greenfield JP, Lyden D, De Braganca KD, Gilheeney SW, Larson SM, Cheung NV.Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26754. Epub 2017 Sep 22.

PMID:28940863

PEDIATRIC BLOOD CANCER – SEPTEMBER 2017

A phase II study of radioimmunotherapy with intraventricular ¹³¹ I-3F8 for medulloblastoma.

PMID: 28940863

PALLIATIVE SUPPORT CARE – SEPTEMBER 2017

Rapid autopsy of a patient with recurrent anaplastic ependymoma.

Lange KR, Fischer C, Rajappa P, Connors S, Pisapia D, Greenfield JP, Beltran H, Rubin M, Mosquera JM, Khakoo Y. Palliat Support Care. 2018 Apr;16(2):238-242. doi: 10.1017/S1478951517000864. Epub 2017 Sep 25.

PMID: 28942746 Free PMC Article

JCO PRECISION ONCOLOGY – JUNE 2017

Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.

Pisapia DJ, Salvatore S, Pauli C, Hissong E, Eng K, Prandi D, Sailer VW, Robinson BD, Park K, Cyrta J, Tagawa ST, Kossai M, Fontugne J, Kim R, Sigaras A, Rao R, Pancirer D, Faltas B, Bareja R, Molina AM, Nanus DM, Rajappa P, Souweidane MM, Greenfield J, Emde AK, Robine N, Elemento O, Sboner A, Demichelis F, Beltran H, Rubin MA, Mosquera JM.JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.16.00038. Epub 2017 Jun 14.

PMID: 29333526 . Free PMC Article

CLINICAL CANCER RESEARCH – JUNE 2017

Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells.

Rajappa P, Cobb WS, Vartanian E, Huang Y, Daly L, Hoffman C, Zhang J, Shen B, Yanowitch R, Garg K, Cisse B, Haddock S, Huse J, Pisapia DJ, Chan TA, Lyden DC, Bromberg JF, Greenfield JP.

PMID:28039266

JOURNAL OF CLINICAL INVESTIGATION – MAY 2017

A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.

Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, Matei I, Peinado H, Bromberg J, Holland E, Ding BS, Rafii S, Lyden D, Greenfield J.

PMID:28394259

CANCER RESEARCH – APRIL 2017

Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.

Kossatz S, Carney B, Schweitzer M, Carlucci G, Miloushev VZ, Maachani UB, Rajappa P, Keshari KR, Pisapia D, Weber WA, Souweidane MM, Reiner T.

PMID:28108511

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ALL ACADEMIC PUBLICATIONS